Action of L-α-methyldopa-hydrazine on the blood pressure of patients receiving levodopa
Identifieur interne : 000504 ( Main/Exploration ); précédent : 000503; suivant : 000505Action of L-α-methyldopa-hydrazine on the blood pressure of patients receiving levodopa
Auteurs : D. B. Calne ; A. Petrie ; Sumant Rao ; J. L. Reid ; S. D. VakilSource :
- British Journal of Pharmacology [ 0007-1188 ] ; 1972.
Abstract
The blood pressure and pulse rate have been compared in a 'double blind, cross over' study involving twenty patients with idiopathic Parkinsonism receiving maximum tolerated dosage of levodopa with and without an extracerebral decarboxylase inhibitor, L-α-methyldopahydrazine. The supine and erect systolic pressures were significantly higher and the erect pulse rate significantly lower during administration of L-α-methyldopahydrazine. The implications of these observations are discussed.
Url:
PubMed: 5015036
PubMed Central: 1665682
Affiliations:
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Le document en format XML
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